Monday 08 December 2025
BE Biomedical Engineering FYDP 2025-2026
Stream 1. Computational Fluid Dynamics in Blood Flow
These projects involve foundational Computational Fluid Dynamics (CFD) modeling using commercial or open-source software (like ANSYS Fluent, OpenFOAM, or even MATLAB-based fluid simulators).
Project 1.1. CFD Analysis of Carotid Artery Stenosis
Model steady-state blood flow through a simplified, idealized carotid artery with varying degrees of stenosis (narrowing). Calculate and visualize the change in pressure drop and Wall Shear Stress (WSS) as the narrowing increases from 30% to 70%. Relate results to the risk of plaque rupture.
Project 1.2. Aortic Coarctation Hemodynamics
Simulate flow through a simplified aortic coarctation (a congenital narrowing of the aorta). Compare the velocity profiles and turbulence levels upstream and downstream of the coarctation. Determine the optimal mesh resolution required for accurate turbulence modeling.
Project 1.3. Non-Newtonian Fluid Model in Small Vessels
Investigate the effect of modeling blood as a non-Newtonian fluid (e.g., using the Casson or power-law model) versus a simple Newtonian fluid in a small capillary or arteriole. Perform 2D simulations for both models and quantify the difference in the velocity profiles and viscosity distribution.
Steam 2. Cyber Physical Systems (CPS) in Medical IoT
These projects focus on integrating physical medical devices with computational and network infrastructure, typical of Medical Internet of Things (MIoT).
Project 2.1. Smart Vitals Monitoring Patch (CPS Design)
Design and prototype a low-power, integrated system for continuous monitoring of basic vitals (e.g., heart rate, skin temperature). Physical System: Select and integrate appropriate sensors (e.g., ECG, PPG, thermistor). Cyber System: Develop embedded software (e.g., using Arduino/Raspberry Pi) for data acquisition and local processing. Connectivity: Implement a basic wireless communication protocol (Bluetooth/Wi-Fi) to stream encrypted data to a mobile application or cloud service (the "cyber" layer).
Project 2.2. Intelligent Drug Dispenser with Inventory Tracking
Develop a prototype for a smart medication dispenser that tracks user adherence and monitors the remaining pill inventory. Use weight sensors or optical sensors to detect dispensing events and inventory level. Integrate a real-time clock and a notification system (e.g., LED lights, buzzer, or SMS/email alerts via a gateway) to prompt the user and report non-adherence.
Project 2.3. Wearable Fall Detection and Alert System
Create a CPS that detects a patient fall and automatically alerts a caregiver. Use an accelerometer/gyroscope on a wearable device to detect the characteristic motion pattern of a fall. Implement a robust signal processing algorithm (e.g., thresholding, machine learning classification) and integrate the system with a communication module to send geo-location data and an alert message.
Steam 3. Quantum Computing in Biosensors (Conceptual/Simulated)
Given the complexity and hardware requirements of true quantum computing, undergraduate projects in this area typically focus on simulating quantum concepts or applying quantum-inspired algorithms to biosensing data.
Project 3.1. Quantum-Inspired Optimization for Sensor Placement
Apply a quantum annealing or quantum-inspired optimization algorithm(simulated on a classical computer) to solve a complex optimization problem in biosensor design, such as optimal placement of sensors on the body or within a microfluidic chip. Formulate the sensor placement as an Ising model or Quadratic Unconstrained Binary Optimization (QUBO) problem and use an open-source library (like D-Wave's Ocean tools or similar classical simulators) to find the best configuration.
Project 3.2. Modeling of a Quantum Dot Biosensor (Focus on Sensing Mechanism)
Develop a theoretical or computational model for a Quantum Dot (QD)-based biosensor to analyze how its quantum properties (e.g., photoluminescence spectrum) change upon binding with a target molecule (e.g., a specific protein). Use computational chemistry or quantum mechanical simulation tools (like Gaussian, VASP, or simpler online tools) to model the energy levels and optical properties of the QD with and without the binding analyte.
Project 3.3. Quantum Machine Learning for ECG Classification (Simulated)
Implement a simulated Quantum Machine Learning (QML) algorithm, such as a Quantum Support Vector Machine (QSVM), to classify simple ECG patterns (e.g., normal vs. atrial fibrillation). Use an open-source quantum programming framework (like Qiskit or Cirq) to train a small-scale model on a simplified dataset of pre-processed ECG features, demonstrating the potential for quantum speedup in medical diagnostics.
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